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CS-W001157 4
Total: USD 88.00

(S)-tert-Butyl (2-(methylamino)propyl)carbamate

  • CAS No. 454709-95-6

  • Cat. No. CS-D0163
  • Purity≥97%
  • MDL No.MFCD18831339

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl (2-(methylamino)propyl)carbamate|CS-D0163

Structure of 454709-95-6

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General Information

  • CAS No. 454709-95-6
  • Cat. No. CS-D0163
  • Purity ≥97%
  • MDL No. MFCD18831339
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₀N₂O₂
  • Molecular Weight 188.27
  • Synonym(s) Carbamic acid, [(2S)-2-(methylamino)propyl]-, 1,1-dimethylethyl ester (9CI)
  • SMILES O=C(OC(C)(C)C)NC[C@@H](NC)C

Description

(S)-tert-Butyl (2-(methylamino)propyl)carbamate is a chiral building block featuring a stereodefined amine handle and a robust carbamate protecting group. This configuration enables direct incorporation into peptide synthesis workflows, where the methylamino side chain supports efficient derivatization and orthogonal deprotection under mild conditions. The tert-butyl carbamate moiety ensures stability during handling and purification.

Application

(S)-tert-Butyl (2-(methylamino)propyl)carbamate serves as a chiral building block for the synthesis of bioactive amines and peptidomimetics. Its tert-butyl carbamate group provides excellent stability and ease of removal under mild acidic conditions, while the (S)-configured secondary amine enables stereoselective transformations. The molecule functions effectively in standard coupling reactions and supports the construction of complex heterocyclic scaffolds relevant to medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.119
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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