Lot numbers can be found on the outside label of a product:
(R)-tert-Butyl (1-aminopropan-2-yl)carbamate
-
CAS No. 100927-10-4
- Cat. No. CS-W018741
- Purity≥95%
- MDL No.MFCD11112229
*For research and further manufacturing use only, not for direct human use.
Structure of 100927-10-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 100927-10-4
- Cat. No. CS-W018741
- Purity ≥95%
- MDL No. MFCD11112229
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₈N₂O₂
- Molecular Weight 174.24
- Synonym(s) Carbamic acid, [(1R)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)
- SMILES O=C(OC(C)(C)C)N[C@H](C)CN
Description
(R)-tert-Butyl (1-aminopropan-2-yl)carbamate is a chiral building block featuring a stereodefined secondary amine and a robust tert-butyloxycarbonyl (Boc) protecting group. This configuration enables selective coupling in asymmetric synthesis, particularly for peptidomimetics and bioactive intermediates. The molecule exhibits excellent stability under standard bench conditions and facilitates straightforward deprotection to reveal the free amine.
Application
(R)-tert-Butyl (1-aminopropan-2-yl)carbamate serves as a chiral, bench-stable amino protecting group precursor for the synthesis of (R)-configured amino alcohols and β-amino acid derivatives. It facilitates efficient N–C bond formation in peptide coupling and asymmetric synthesis, with high functional group tolerance and straightforward deprotection under mild acidic conditions. Its robustness and stereochemical integrity make it a reliable building block for complex molecular scaffolds in medicinal chemistry workflows.
Synthesis
-
Route1
-
1352719-38-0 - ~%
-
In-stock
100927-10-4
References
-
Bioscience, Biotechnology and Biochemistry, , vol. 75, # 4 p. 780 - 782
-
-
Route2
-
In-stock
79069-13-9 - ~%
-
In-stock
100927-10-4
References
-
Bioscience, Biotechnology and Biochemistry, , vol. 75, # 4 p. 780 - 782
-
-
Route3
-
721927-55-5
- ~%
-
In-stock
100927-10-4
References
-
WO2006/116764 A1, ; Page/Page column 123 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 64.35
- LogP 0.8583
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 100927-10-4 sigma100927-10-4 manufacturer100927-10-4 price100927-10-4 structure100927-10-4 SDSbuy 100927-10-4100927-10-4 supplier100927-10-4 uses100927-10-4 molecular weightprice of 100927-10-4100927-10-4 chemical name formula of 100927-10-4