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Structure of 453562-71-5
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1-(6-Amino-3,3-dimethylindolin-1-yl)ethanone features a sterically hindered indolinone core with a pendant amino group, enabling direct integration into peptide and heterocyclic scaffolds. The acetyl moiety provides a reactive handle for derivatization under mild conditions, while the electron-rich aromatic system enhances solubility in polar organic solvents. This compound serves as a key building block for bioactive molecule synthesis.
1-(6-Amino-3,3-dimethylindolin-1-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling the construction of indoline-based scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. The acetamide functionality provides a handle for derivatization via acylation or reductive amination, while the 3,3-dimethyl substitution enhances metabolic stability and modulates solubility. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: