Methyl 4-bromo-3-fluorobenzoate

Name: Methyl 4-bromo-3-fluorobenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 849758-12-9
Cat. No. CS-W005414
Purity≥98%
MDL No.MFCD08436044

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-bromo-3-fluorobenzoate|CS-W005414

Structure of 849758-12-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 849758-12-9
Cat. No. CS-W005414
Purity ≥98%
MDL No. MFCD08436044
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆BrFO₂
Molecular Weight 233.03
Synonym(s) 4-Bromo-3-fluorobenzoic Acid Methyl Ester
SMILES O=C(OC)C1=CC=C(Br)C(F)=C1

Description

Methyl 4-bromo-3-fluorobenzoate features a strategically positioned bromo and fluoro substituent on the aromatic ring, enabling selective coupling reactions in cross-coupling and functionalization workflows. The ester group provides a handle for further derivatization, while the electron-withdrawing halogens enhance reactivity in palladium-catalyzed transformations. This compound serves as a key intermediate in medicinal chemistry and materials science applications.

Application

Methyl 4-bromo-3-fluorobenzoate serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, or Negishi coupling, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Its bench-stable nature and straightforward purification support scalable synthesis of complex aromatic architectures.

Synthesis

Route1
- 67-56-1
- In-stock
  
  153556-42-4
- ~99%
- In-stock
  
  849758-12-9
References
- Liang, Chungen; Tang, Guozhi; Wong, Jason Christopher; Wu, Xihan; Zhang, Zhenshan Patent: US2010/216806 A1, 2010 ; Location in patent: Page/Page column 103 ;
Route2
- In-stock
  
  153556-42-4
- 18107-18-1
- ~94%
- In-stock
  
  849758-12-9
References
- Medivir AB; IVANOV, Vladimir; SAMUELSSON, Bertil; JOHANSSON, Per-Ola; KAHNBERG, Pia; WAeHLING, Horst Patent: WO2010/34789 A1, 2010 ; Location in patent: Page/Page column 24 ; WO 2010/034789 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 26.3
LogP 2.3748
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 4-bromo-3-fluorobenzoate sigmaMethyl 4-bromo-3-fluorobenzoate manufacturerMethyl 4-bromo-3-fluorobenzoate priceMethyl 4-bromo-3-fluorobenzoate structureMethyl 4-bromo-3-fluorobenzoate SDSbuy Methyl 4-bromo-3-fluorobenzoateMethyl 4-bromo-3-fluorobenzoate supplierMethyl 4-bromo-3-fluorobenzoate usesMethyl 4-bromo-3-fluorobenzoate molecular weightprice of Methyl 4-bromo-3-fluorobenzoateMethyl 4-bromo-3-fluorobenzoate chemical name formula of Methyl 4-bromo-3-fluorobenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-bromo-3-fluorobenzoate

CAS No. 849758-12-9

Recommended Products