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(S)-2-((tert-Butoxycarbonyl)amino)-5-ureidopentanoic acid

  • CAS No. 45234-13-7

  • Cat. No. CS-0059158
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-((tert-Butoxycarbonyl)amino)-5-ureidopentanoic acid|CS-0059158

Structure of 45234-13-7

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General Information

  • CAS No. 45234-13-7
  • Cat. No. CS-0059158
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁N₃O₅
  • Molecular Weight 275.30
  • Synonym(s) N~2~-(tert-butoxycarbonyl)-N~5~-carbamoyl-L-ornithine
  • SMILES O=C(O)[C@H](CCCNC(N)=O)NC(OC(C)(C)C)=O

Description

(S)-2-((tert-Butoxycarbonyl)amino)-5-ureidopentanoic acid features a chiral center at the α-position, bearing a tert-butoxycarbonyl-protected amine and a terminal ureido group. This bifunctional scaffold integrates a masked amine with a polar urea moiety, enabling selective conjugation in peptide synthesis and bioconjugation workflows under standard conditions.

Application

(S)-2-((tert-Butoxycarbonyl)amino)-5-ureidopentanoic acid serves as a versatile building block for the synthesis of peptide-based scaffolds and bioactive heterocycles. The Boc-protected amine and terminal ureido group enable sequential functionalization, offering compatibility with standard coupling protocols and orthogonal deprotection strategies. Its bench-stable nature and clean purification profile make it well-suited for iterative solid-phase and solution-phase syntheses in medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   130.75
  • LogP   0.4128
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   6

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