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CS-W001157 4
Total: USD 88.00

Fmoc-α-Me-Leu-OH

  • CAS No. 312624-65-0

  • Cat. No. CS-0101075
  • Purity≥96%
  • MDL No.MFCD08458572

*For research and further manufacturing use only, not for direct human use.

Fmoc-α-Me-Leu-OH|CS-0101075

Structure of 312624-65-0

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General Information

  • CAS No. 312624-65-0
  • Cat. No. CS-0101075
  • Purity ≥96%
  • MDL No. MFCD08458572
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₅NO₄
  • Molecular Weight 367.44
  • Synonym(s) None
  • SMILES CC(C)C[C@](C(O)=O)(C)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

Fmoc-α-Me-Leu-OH is a sterically hindered, bench-stable amino acid derivative featuring a methylated α-carbon that enhances resistance to racemization. This configuration improves coupling efficiency in solid-phase peptide synthesis, particularly for challenging sequences. The Fmoc group enables orthogonal protection, facilitating stepwise chain elongation with high fidelity and minimal side reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.4145
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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