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CS-W001157 4
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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methoxy-L-phenylalanine

  • CAS No. 206060-40-4

  • Cat. No. CS-0040949
  • Purity≥97%
  • MDL No.MFCD01317009

*For research and further manufacturing use only, not for direct human use.

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methoxy-L-phenylalanine|CS-0040949

Structure of 206060-40-4

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General Information

  • CAS No. 206060-40-4
  • Cat. No. CS-0040949
  • Purity ≥97%
  • MDL No. MFCD01317009
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₃NO₅
  • Molecular Weight 417.45
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CC1=CC=CC(OC)=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

Fmoc-3-methoxy-L-phenylalanine is a protected amino acid derivative featuring a fluorenylmethyl carbamate (Fmoc) group for orthogonal handling in peptide synthesis. The methoxy-substituted phenyl side chain enhances solubility and modulates electronic properties, enabling efficient incorporation into complex sequences under standard conditions.

Application

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methoxy-L-phenylalanine serves as a protected amino acid building block for peptide synthesis, enabling efficient incorporation of a methoxy-substituted phenylalanine residue. The Fmoc group provides orthogonal protection with high stability under basic conditions and facile removal via mild base treatment. The 3-methoxyphenyl side chain offers enhanced lipophilicity and metabolic stability, making this derivative valuable in the construction of bioactive peptides and peptidomimetics.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   4.2296
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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