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CS-W001157 4
Total: USD 88.00

6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole

  • CAS No. 444731-74-2

  • Cat. No. CS-B0768
  • Purity≥96%
  • MDL No.MFCD17014818

*For research and further manufacturing use only, not for direct human use.

6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole|CS-B0768

Structure of 444731-74-2

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General Information

  • CAS No. 444731-74-2
  • Cat. No. CS-B0768
  • Purity ≥96%
  • MDL No. MFCD17014818
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂ClN₅
  • Molecular Weight 273.72
  • Synonym(s) N-(2-Chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine; N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl-2H-Indazol-6-amine
  • SMILES CC1=C2C=CC(NC3=NC(Cl)=NC=C3)=CC2=NN1C

Synthesis

  • Route1
    • null|null
      3934-20-1
    • 2,3-Dimethyl-6-amino-2H-indazole Pazopanib  Impurity|CS-0229218
      444731-72-0
    • ~98%
    • In-stock
      6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole|CS-B0768
      444731-74-2

    References

    • Chemical Biology and Drug Design, , vol. 83, # 3 p. 306 - 316
  • Route2
    • null|null
      3934-20-1
    • In-stock
      2,3-Dimethyl-2H-indazol-6-amine hydrochloride|CS-0052175
      635702-60-2
    • ~88%
    • In-stock
      6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole|CS-B0768
      444731-74-2

    References

    • Journal of Medicinal Chemistry, , vol. 51, # 15 p. 4632 - 4640
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 4 p. 1108 - 1110

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.63
  • LogP   3.06872
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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