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CS-W001157 4
Total: USD 88.00

tert-Butyl (3-(methylamino)propyl)carbamate

  • CAS No. 442514-22-9

  • Cat. No. CS-B0432
  • Purity≥95%
  • MDL No.MFCD06808586

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3-(methylamino)propyl)carbamate|CS-B0432

Structure of 442514-22-9

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General Information

  • CAS No. 442514-22-9
  • Cat. No. CS-B0432
  • Purity ≥95%
  • MDL No. MFCD06808586
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₀N₂O₂
  • Molecular Weight 188.27
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCNC

Description

tert-Butyl (3-(methylamino)propyl)carbamate features a protected amine handle ideal for peptide synthesis and bioconjugation. The tert-butyl carbamate group enables mild deprotection under acidic conditions, while the pendant methylaminoalkyl chain offers enhanced solubility and reactivity in polar media. This derivative integrates readily into multifunctional scaffolds.

Application

tert-Butyl (3-(methylamino)propyl)carbamate serves as a versatile aminoalkyl protecting group precursor, enabling selective introduction of primary amine functionalities under mild conditions. Its tert-butyl carbamate moiety provides excellent bench stability and facilitates straightforward deprotection with trifluoroacetic acid. The molecule exhibits strong functional group tolerance and is widely employed in the synthesis of bioactive heterocycles and peptide derivatives, particularly in medicinal chemistry campaigns requiring efficient amine handling and orthogonal protection strategies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.1206
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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