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CS-W001157 4
Total: USD 88.00

tert-Butyl 4-(methylamino)butylcarbamate

  • CAS No. 874831-66-0

  • Cat. No. CS-B0433
  • Purity≥96%
  • MDL No.MFCD06808587

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(methylamino)butylcarbamate|CS-B0433

Structure of 874831-66-0

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General Information

  • CAS No. 874831-66-0
  • Cat. No. CS-B0433
  • Purity ≥96%
  • MDL No. MFCD06808587
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₂N₂O₂
  • Molecular Weight 202.30
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCCNC

Description

tert-Butyl 4-(methylamino)butylcarbamate features a protected amine handle ideal for peptide synthesis and bioconjugation. The tert-butyl carbamate group enables selective deprotection under mild acidic conditions, while the primary methylaminoalkyl side chain offers a reactive site for coupling. This stable, bench-ready reagent integrates seamlessly into diverse molecular architectures.

Application

tert-Butyl 4-(methylamino)butylcarbamate serves as a versatile bifunctional building block in medicinal chemistry, enabling the synthesis of bioactive amines and heterocyclic scaffolds. The tert-butyl carbamate (Boc) group provides stable protection under basic conditions and mild acidic deprotection, while the primary amine functionality facilitates conjugation reactions. Its methylamino substituent enhances solubility and metabolic stability in downstream analogs, making it ideal for iterative synthesis workflows requiring orthogonal functionalization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.5107
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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