(R)-1-Boc-pyrrolidine-1,3-dicarboxylate

Name: (R)-1-Boc-pyrrolidine-1,3-dicarboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 441717-40-4
Cat. No. CS-B0424
Purity≥98%
MDL No.MFCD09954284

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-1-Boc-pyrrolidine-1,3-dicarboxylate|CS-B0424

Structure of 441717-40-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 441717-40-4
Cat. No. CS-B0424
Purity ≥98%
MDL No. MFCD09954284
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₉NO₄
Molecular Weight 229.27
Synonym(s) (R)-1-tert-butyl 3-methyl pyrrolidine-1,3-dicarboxylate
SMILES O=C(OC(C)(C)C)N(CC1)C[C@@H]1C(OC)=O

Description

(R)-1-Boc-pyrrolidine-1,3-dicarboxylate features a stereochemically defined pyrrolidine core with orthogonal Boc and dicarboxylate functionalities. This configuration enables selective derivatization in asymmetric synthesis, particularly in peptide mimetics and catalyst design. The protected amine and stable ester groups facilitate sequential functionalization under standard conditions.

Application

(R)-1-Boc-pyrrolidine-1,3-dicarboxylate serves as a key chiral building block in asymmetric synthesis, enabling efficient access to pyrrolidine-containing scaffolds. The Boc group provides excellent stability and ease of removal under mild acidic conditions, while the 1,3-dicarboxylate functionality supports orthogonal derivatization. This compound facilitates diverse transformations including reductive amination, cross-coupling, and heterocycle formation, making it highly valuable for medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  72925-16-7
- 18107-18-1
- ~%
- In-stock
  
  441717-40-4
References
- WO2007/70398 A1, ; Page/Page column 188 ; WO 2007/070398 A1
Route2
- 67-56-1
- In-stock
  
  72925-16-7
- ~%
- In-stock
  
  441717-40-4
- In-stock
  
  313706-15-9
- In-stock
  
  72925-16-7
- In-stock
  
  140148-70-5
References
- Organic Process Research and Development, , vol. 13, # 2 p. 292 - 296

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 55.84
LogP 1.4164
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

(R)-1-Boc-pyrrolidine-1,3-dicarboxylate sigma(R)-1-Boc-pyrrolidine-1,3-dicarboxylate manufacturer(R)-1-Boc-pyrrolidine-1,3-dicarboxylate price(R)-1-Boc-pyrrolidine-1,3-dicarboxylate structure(R)-1-Boc-pyrrolidine-1,3-dicarboxylate SDSbuy (R)-1-Boc-pyrrolidine-1,3-dicarboxylate(R)-1-Boc-pyrrolidine-1,3-dicarboxylate supplier(R)-1-Boc-pyrrolidine-1,3-dicarboxylate uses(R)-1-Boc-pyrrolidine-1,3-dicarboxylate molecular weightprice of (R)-1-Boc-pyrrolidine-1,3-dicarboxylate(R)-1-Boc-pyrrolidine-1,3-dicarboxylate chemical name formula of (R)-1-Boc-pyrrolidine-1,3-dicarboxylate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-1-Boc-pyrrolidine-1,3-dicarboxylate

CAS No. 441717-40-4

Recommended Products