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CS-W001157 4
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1-Methyl-4-(piperidin-4-yl)piperazine hydrochloride

  • CAS No. 436099-90-0

  • Cat. No. CS-W005113
  • Purity≥97%
  • MDL No.MFCD06801088

*For research and further manufacturing use only, not for direct human use.

1-Methyl-4-(piperidin-4-yl)piperazine hydrochloride|CS-W005113

Structure of 436099-90-0

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General Information

  • CAS No. 436099-90-0
  • Cat. No. CS-W005113
  • Purity ≥97%
  • MDL No. MFCD06801088
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₂ClN₃
  • Molecular Weight 219.76
  • Synonym(s) 1-Methyl-4-piperidin-4-yl-piperazinehydrochloride
  • SMILES CN1CCN(C2CCNCC2)CC1.[H]Cl

Description

1-Methyl-4-(piperidin-4-yl)piperazine hydrochloride features a bifunctional piperazine core with a methylated nitrogen and a secondary piperidine ring, enabling strong hydrogen bonding and enhanced solubility. This bench-stable salt form facilitates handling in synthetic workflows and supports efficient incorporation into bioactive molecules for medicinal chemistry applications.

Application

1-Methyl-4-(piperidin-4-yl)piperazine hydrochloride serves as a versatile nitrogen-rich heterocyclic building block, enabling efficient access to complex pharmacophores in medicinal chemistry. Its dual piperazine and piperidine moieties offer enhanced solubility, functional group tolerance, and compatibility with standard coupling and derivatization protocols. The hydrochloride salt ensures excellent bench stability and ease of handling, facilitating straightforward purification and integration into multi-step synthetic sequences for API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.51
  • LogP   0.4076
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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