Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(S)-4-Oxopyrrolidine-2-carboxylic acid

  • CAS No. 4347-18-6

  • Cat. No. CS-0271190
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-4-Oxopyrrolidine-2-carboxylic acid|CS-0271190

Structure of 4347-18-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4347-18-6
  • Cat. No. CS-0271190
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇NO₃
  • Molecular Weight 129.11
  • Synonym(s) 4-Oxo-L-proline
  • SMILES C1C(=O)CN[C@@H]1C(=O)O

Description

(S)-4-Oxopyrrolidine-2-carboxylic acid is a chiral pyrrolidine derivative featuring a ketone at the C4 position and a carboxylic acid at C2. This configuration imparts distinct stereochemical control in asymmetric synthesis, enabling its use as a building block for bioactive molecules. The molecule's rigid, electron-deficient ring system enhances binding affinity in peptidomimetic applications, while its bench-stable nature simplifies handling under standard conditions.

Application

(S)-4-Oxopyrrolidine-2-carboxylic acid serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to pyrrolidine-based pharmacophores. Its enantiopure structure facilitates stereoselective synthesis of bioactive molecules, particularly in the construction of constrained peptidomimetics and heterocyclic scaffolds. The molecule exhibits good bench stability, tolerates common functional groups, and participates reliably in amide coupling, reduction, and cyclization reactions under standard conditions.

Synthesis

  • Route1

    References

    • Patchett; Witkop Journal of the American Chemical Society, 1957 , vol. 79, p. 185,190
  • Route2

    References

    • Patchett; Witkop Journal of the American Chemical Society, 1957 , vol. 79, p. 185,190
  • Route3

    References

    • Patchett; Witkop Journal of the American Chemical Society, 1957 , vol. 79, p. 185,190

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   66.4
  • LogP   -0.998
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • (S)-4-Oxopyrrolidine-2-carboxylic acid sigma(S)-4-Oxopyrrolidine-2-carboxylic acid manufacturer(S)-4-Oxopyrrolidine-2-carboxylic acid price(S)-4-Oxopyrrolidine-2-carboxylic acid structure(S)-4-Oxopyrrolidine-2-carboxylic acid SDSbuy (S)-4-Oxopyrrolidine-2-carboxylic acid(S)-4-Oxopyrrolidine-2-carboxylic acid supplier(S)-4-Oxopyrrolidine-2-carboxylic acid uses(S)-4-Oxopyrrolidine-2-carboxylic acid molecular weightprice of (S)-4-Oxopyrrolidine-2-carboxylic acid(S)-4-Oxopyrrolidine-2-carboxylic acid chemical name formula of (S)-4-Oxopyrrolidine-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label