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CS-W001157 4
Total: USD 88.00

(S)-4-oxopyrrolidine-2-carboxylic acid hydrochloride

  • CAS No. 54615-47-3

  • Cat. No. CS-0476427
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-4-oxopyrrolidine-2-carboxylic acid hydrochloride|CS-0476427

Structure of 54615-47-3

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General Information

  • CAS No. 54615-47-3
  • Cat. No. CS-0476427
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈ClNO₃
  • Molecular Weight 165.57
  • Synonym(s) None
  • SMILES OC([C@@H]1CC(CN1)=O)=O.Cl

Description

(S)-4-oxopyrrolidine-2-carboxylic acid hydrochloride features a stereochemically defined pyrrolidinone core with enhanced solubility and stability under standard conditions. This bench-stable derivative serves as a key chiral building block in the synthesis of bioactive heterocycles, particularly in peptide-based drug candidates where precise stereocontrol is essential.

Application

(S)-4-Oxopyrrolidine-2-carboxylic acid hydrochloride serves as a key chiral building block in the synthesis of pyrrolidine-containing pharmaceuticals and natural products. Its well-defined stereochemistry and stable carbonyl functionality enable reliable incorporation into diverse heterocyclic scaffolds. The hydrochloride salt enhances solubility and handling stability, facilitating use in standard peptide coupling and reductive amination protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   -0.5762
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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