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Structure of 43083-14-3
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2-Chloro-6-phenylnicotinonitrile features a sterically hindered nitrile group flanked by a chlorine substituent and a phenyl ring, enabling robust integration into heterocyclic frameworks. This electron-deficient pyridine core facilitates efficient coupling reactions under standard conditions, delivering high yields in cross-coupling and cyclization processes.
2-Chloro-6-phenylnicotinonitrile serves as a versatile building block in the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its ortho-chloro and cyano groups enable directed metalation, cross-coupling reactions, and nucleophilic transformations under standard conditions. The phenyl substituent provides structural rigidity and enhanced solubility, while the molecule exhibits good bench stability and compatibility with common reaction protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: