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CS-W001157 4
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2-Oxo-2,3-dihydrothiazole-4-carboxylic acid

  • CAS No. 43029-06-7

  • Cat. No. CS-0530108
  • Molecule weight145.14
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Oxo-2,3-dihydrothiazole-4-carboxylic acid|CS-0530108

Structure of 43029-06-7

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General Information

  • CAS No. 43029-06-7
  • Cat. No. CS-0530108
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃NO₃S
  • Molecular Weight 145.14
  • Synonym(s) 2-Oxo-2,3-dihydro-1,3-thiazole-4-carboxylic acid
  • SMILES O=C(C1=CSC(N1)=O)O

Description

This thiazole derivative features a conjugated keto-carboxylic acid motif, enabling direct integration into heterocyclic scaffolds. The electron-deficient ring system facilitates nucleophilic substitution and serves as a versatile synthon in medicinal chemistry. Bench-stable under standard conditions, it streamlines access to bioactive thiazole-based compounds.

Application

2-Oxo-2,3-dihydrothiazole-4-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds through controlled cyclization and functional group manipulation. Its carboxylic acid functionality facilitates direct coupling reactions, while the enone-like structure supports nucleophilic addition and metal-catalyzed transformations. The compound exhibits bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   70.16
  • LogP   0.1346
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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