Lot numbers can be found on the outside label of a product:
2,3-Dihydroquinolin-4(1H)-one
-
CAS No. 4295-36-7
- Cat. No. CS-W005292
- Purity≥95%
- MDL No.MFCD00666394
*For research and further manufacturing use only, not for direct human use.
Structure of 4295-36-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 4295-36-7
- Cat. No. CS-W005292
- Purity ≥95%
- MDL No. MFCD00666394
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₉NO
- Molecular Weight 147.17
- Synonym(s) 2,3-dihydro-1H-quinolin-4-one
- SMILES O=C1CCNC2=C1C=CC=C2
Description
2,3-Dihydroquinolin-4(1H)-one features a fused bicyclic scaffold with a lactam carbonyl and saturated C2–C3 bond, offering enhanced stability and solubility in polar solvents. This core structure integrates readily into synthetic routes for bioactive molecules, particularly in medicinal chemistry campaigns targeting kinase inhibitors and CNS modulators. The system’s electron-rich aromatic ring supports efficient functionalization at C6 and C7 positions.
Application
2,3-Dihydroquinolin-4(1H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard functionalization at the C2 and C3 positions. Its bench-stable nature and compatibility with common coupling reactions facilitate rapid diversification. Functions as a key building block for synthesizing substituted quinolines and analogs relevant to kinase inhibitors and CNS-targeted therapeutics.
Synthesis
-
Route1
-
In-stock
5652-38-0 - ~72%
-
In-stock
4295-36-7
References
-
Bellassoued-Fargeau, Marie-Claude; Graffe, Bernadette; Sacquet, Marie-Claude; Maitte, P. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 713 - 718
-
-
Route2
-
In-stock
5099-95-6 - ~97%
-
In-stock
4295-36-7
References
-
Lange, Jens; Bissember, Alex C.; Banwell, Martin G.; Cade, Ian A. Australian Journal of Chemistry, 2011 , vol. 64, # 4 p. 454 - 470
-
-
Route3
-
62750-11-2 - ~67%
-
In-stock
4295-36-7
References
-
Schering Corporation Patent: US2011/312995 A1, 2011 ; Location in patent: Page/Page column 50 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 29.1
- LogP 1.6849
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2,3-Dihydroquinolin-4(1H)-one sigma2,3-Dihydroquinolin-4(1H)-one manufacturer2,3-Dihydroquinolin-4(1H)-one price2,3-Dihydroquinolin-4(1H)-one structure2,3-Dihydroquinolin-4(1H)-one SDSbuy 2,3-Dihydroquinolin-4(1H)-one2,3-Dihydroquinolin-4(1H)-one supplier2,3-Dihydroquinolin-4(1H)-one uses2,3-Dihydroquinolin-4(1H)-one molecular weightprice of 2,3-Dihydroquinolin-4(1H)-one2,3-Dihydroquinolin-4(1H)-one chemical name formula of 2,3-Dihydroquinolin-4(1H)-one