(S)-Piperidin-2-ylmethanol

Name: (S)-Piperidin-2-ylmethanol
Brand: ChemScene
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CAS No. 41373-39-1
Cat. No. CS-W001568
Purity≥97%
MDL No.MFCD11036291

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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General Information

CAS No. 41373-39-1
Cat. No. CS-W001568
Purity ≥97%
MDL No. MFCD11036291
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO
Molecular Weight 115.17
Synonym(s) ((S)-PIPERIDIN-2-YL)METHANOL
SMILES OC[C@@H]1CCCCN1

Description

(S)-Piperidin-2-ylmethanol is a chiral building block featuring a stereodefined secondary alcohol within a piperidine scaffold. This configuration imparts distinct reactivity and binding affinity in asymmetric synthesis, particularly for medicinal chemistry applications. The hydroxymethyl group enables facile derivatization through etherification or oxidation, while the basic nitrogen supports salt formation and coordination in catalytic systems. Bench-stable and readily handled under standard conditions, it serves as a key intermediate in the development of bioactive molecules.

Application

(S)-Piperidin-2-ylmethanol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established functional group transformations. Its bench-stable nature and compatibility with standard coupling and reduction protocols facilitate efficient access to piperidine-based scaffolds. Functions as a key intermediate in the construction of heterocyclic APIs and targeted drug candidates.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 32.26
LogP 0.1208
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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(S)-Piperidin-2-ylmethanol

CAS No. 41373-39-1

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