(R)-Piperidin-2-ylmethanol

Name: (R)-Piperidin-2-ylmethanol
Brand: ChemScene
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CAS No. 3197-44-2
Cat. No. CS-W018567
Purity≥95%
MDL No.MFCD11036292

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FedEx Limited Quantities Ground	$0.00
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Structure of 3197-44-2

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General Information

CAS No. 3197-44-2
Cat. No. CS-W018567
Purity ≥95%
MDL No. MFCD11036292
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO
Molecular Weight 115.17
Synonym(s) [(2R)-piperidin-2-yl]methanol
SMILES OC[C@@H]1NCCCC1

Description

(R)-Piperidin-2-ylmethanol is a chiral building block featuring a stereodefined secondary alcohol within a piperidine scaffold. This configuration imparts distinct stereochemical control in asymmetric synthesis, enabling selective functionalization during medicinal chemistry campaigns. The molecule exhibits favorable solubility in common organic solvents and remains bench-stable under standard handling conditions.

Application

(R)-Piperidin-2-ylmethanol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established functional group transformations. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient access to piperidine-containing scaffolds. The stereogenic center supports enantioselective synthesis, while the primary alcohol allows for derivatization via esterification, ether formation, or oxidation—making it a versatile intermediate in API development and target-oriented synthesis.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 32.26
LogP 0.1208
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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(R)-Piperidin-2-ylmethanol

CAS No. 3197-44-2

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