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Structure of 40253-44-9
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Ethyl 5-methyl-1H-imidazole-2-carboxylate features a sterically hindered imidazole core with a methyl group at the C5 position and an ethyl ester at C2. This bench-stable, moisture-tolerant reagent integrates readily into heterocyclic synthesis, serving as a key building block for bioactive nitrogen-rich scaffolds in medicinal chemistry and materials science applications.
Ethyl 5-methyl-1H-imidazole-2-carboxylate serves as a versatile building block for imidazole-based scaffolds, enabling efficient access to pharmaceutically relevant heterocycles. Its stability under standard reaction conditions and compatibility with palladium-catalyzed couplings facilitate straightforward functionalization at the C2 position. The ester group allows for selective hydrolysis or reduction, while the methyl substituent enhances metabolic stability in downstream analogs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: