(R)-1-(Pyridin-3-yl)ethan-1-amine

Name: (R)-1-(Pyridin-3-yl)ethan-1-amine
Brand: ChemScene
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CAS No. 40154-75-4
Cat. No. CS-0029799
Purity≥97%
MDL No.MFCD09256802

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(Pyridin-3-yl)ethan-1-amine|CS-0029799

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General Information

CAS No. 40154-75-4
Cat. No. CS-0029799
Purity ≥97%
MDL No. MFCD09256802
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight 122.17
Synonym(s) (R)-1-Pyridin-3-yl-ethylaMine 2HCl
SMILES N[C@H](C)C1=CC=CN=C1

Description

(R)-1-(Pyridin-3-yl)ethan-1-amine is a chiral amine featuring a pyridine ring directly linked to a stereodefined ethylamine side chain. This configuration enables selective coordination in asymmetric synthesis, while the basic nitrogen and aromatic system facilitate hydrogen bonding and π-stacking interactions. The compound exhibits bench-stable handling under standard conditions and integrates readily into catalytic systems requiring precise stereochemical control.

Application

(R)-1-(Pyridin-3-yl)ethan-1-amine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its pyridyl group provides strong coordination for transition metals, while the chiral amine facilitates asymmetric synthesis. The compound exhibits excellent bench stability, ease of purification, and functional group tolerance, making it well-suited for standard coupling reactions and catalyst development.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 38.91
LogP 1.1013
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(R)-1-(Pyridin-3-yl)ethan-1-amine

CAS No. 40154-75-4

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