(R)-1-(Pyridin-4-yl)ethan-1-amine

Name: (R)-1-(Pyridin-4-yl)ethan-1-amine
Brand: ChemScene
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CAS No. 45682-36-8
Cat. No. CS-0098148
Purity≥97%
MDL No.MFCD09256818

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(Pyridin-4-yl)ethan-1-amine|CS-0098148

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General Information

CAS No. 45682-36-8
Cat. No. CS-0098148
Purity ≥97%
MDL No. MFCD09256818
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight 122.17
Synonym(s) (R)-1-(Pyridin-4-yl)ethanamine dihydrochloride
SMILES C[C@H](C1=CC=NC=C1)N

Description

(R)-1-(Pyridin-4-yl)ethan-1-amine is a chiral amine featuring a pyridyl group at the para position, offering enhanced solubility and defined stereochemistry. This bench-stable compound integrates readily into asymmetric synthesis, serving as a ligand or auxiliary in transition metal catalysis. The stereogenic center enables precise control in enantioselective transformations, particularly in Pd- and Cu-catalyzed couplings.

Application

(R)-1-(Pyridin-4-yl)ethan-1-amine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its pyridyl group facilitates transition metal-catalyzed couplings, while the chiral amine functionality supports stereoselective transformations. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2922
Class : 8(6.1)	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 38.91
LogP 1.1013
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(R)-1-(Pyridin-4-yl)ethan-1-amine

CAS No. 45682-36-8

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