Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Chloro-2-iodopyridin-3-amine

  • CAS No. 400777-06-2

  • Cat. No. CS-W022477
  • Molecule weight254.46
  • Purity≥97%
  • MDL No.MFCD11044246

*For research and further manufacturing use only, not for direct human use.

6-Chloro-2-iodopyridin-3-amine|CS-W022477

Structure of 400777-06-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 400777-06-2
  • Cat. No. CS-W022477
  • Purity ≥97%
  • MDL No. MFCD11044246
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄ClIN₂
  • Molecular Weight 254.46
  • Synonym(s) 3-pyridinamine, 6-chloro-2-iodo-
  • SMILES NC1=CC=C(Cl)N=C1I

Description

6-Chloro-2-iodopyridin-3-amine features a strategically positioned chloro group and iodine handle, enabling selective cross-coupling reactions in medicinal chemistry. The electron-deficient pyridine core enhances reactivity in palladium-catalyzed transformations, while the amine functionality offers direct derivatization potential. This bench-stable scaffold integrates efficiently into complex heterocyclic architectures under standard conditions.

Application

6-Chloro-2-iodopyridin-3-amine serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient access to functionalized pyridine scaffolds. The ortho-chloro and iodo substituents provide complementary reactivity for sequential coupling, while the amino group offers direct derivatization potential. Bench-stable and compatible with standard reaction conditions, it facilitates rapid assembly of complex heterocyclic architectures in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • VERTEX PHARMACEUTICALS INCORPORATED Patent: US2009/253736 A1, 2009 ; Location in patent: Page/Page column 23 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.9218
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Chloro-2-iodopyridin-3-amine sigma6-Chloro-2-iodopyridin-3-amine manufacturer6-Chloro-2-iodopyridin-3-amine price6-Chloro-2-iodopyridin-3-amine structure6-Chloro-2-iodopyridin-3-amine SDSbuy 6-Chloro-2-iodopyridin-3-amine6-Chloro-2-iodopyridin-3-amine supplier6-Chloro-2-iodopyridin-3-amine uses6-Chloro-2-iodopyridin-3-amine molecular weightprice of 6-Chloro-2-iodopyridin-3-amine6-Chloro-2-iodopyridin-3-amine chemical name formula of 6-Chloro-2-iodopyridin-3-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label