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CS-W001157 4
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1-Amino-3-(morpholin-4-yl)propan-2-ol

  • CAS No. 39849-45-1

  • Cat. No. CS-0008405
  • Purity≥97%
  • MDL No.MFCD00462792

*For research and further manufacturing use only, not for direct human use.

1-Amino-3-(morpholin-4-yl)propan-2-ol|CS-0008405

Structure of 39849-45-1

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General Information

  • CAS No. 39849-45-1
  • Cat. No. CS-0008405
  • Purity ≥97%
  • MDL No. MFCD00462792
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆N₂O₂
  • Molecular Weight 160.21
  • Synonym(s) 1-Amino-3-morpholinopropan-2-ol
  • SMILES NCC(O)CN1CCOCC1

Description

1-Amino-3-(morpholin-4-yl)propan-2-ol features a bifunctional scaffold integrating a primary amine and a morpholine ring, enabling robust conjugation and solubility enhancement. This bench-stable compound serves as a versatile building block in medicinal chemistry, where the polar morpholine moiety improves pharmacokinetic properties while the pendant amine facilitates downstream derivatization under standard conditions.

Application

1-Amino-3-(morpholin-4-yl)propan-2-ol serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of bioactive heterocycles and peptide-like scaffolds. Its primary amine and secondary alcohol functionalities offer orthogonal reactivity for conjugation and derivatization. The morpholine ring enhances solubility and modulates physicochemical properties, while the molecule exhibits good bench stability and ease of purification—key advantages in iterative synthesis campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P403-P405-P501

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Computational Chemistry Data

  • TPSA   58.72
  • LogP   -1.3618
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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