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CS-W001157 4
Total: USD 88.00

Phenyl(pyridin-2-yl)methanamine

  • CAS No. 39930-11-5

  • Cat. No. CS-W006043
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Phenyl(pyridin-2-yl)methanamine|CS-W006043

Structure of 39930-11-5

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General Information

  • CAS No. 39930-11-5
  • Cat. No. CS-W006043
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂N₂
  • Molecular Weight 184.24
  • Synonym(s) phenyl(2-pyridyl)methanamine
  • SMILES NC(C1=CC=CC=C1)C2=NC=CC=C2

Description

Phenyl(pyridin-2-yl)methanamine integrates a phenyl ring and a pyridin-2-yl group through a methylene bridge, delivering a rigid, electron-deficient scaffold ideal for ligand design. This bifunctional architecture enables efficient coordination in catalytic systems and facilitates π–π stacking interactions in supramolecular assemblies.

Application

Phenyl(pyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization protocols. Its benzylic amine functionality exhibits robust reactivity in alkylation, acylation, and coupling reactions, while the pyridine moiety provides orthogonal handle for metal coordination and further derivatization. Bench-stable and readily purified by column chromatography or recrystallization, it functions effectively in both small-molecule synthesis and high-throughput screening campaigns.

Synthesis

  • Route1
    • null|null
      1826-28-4
    • ~94%
    • In-stock
      Phenyl(pyridin-2-yl)methanamine|CS-W006043
      39930-11-5

    References

    • Jena, Himanshu Sekhar; Manivannan, Vadivelu Inorganica Chimica Acta, 2013 , vol. 394, p. 210 - 219
  • Route2
    • In-stock
      2-Cyanopyridine|CS-W020084
      100-70-9
    • null|null
      100-58-3
    • ~%
    • In-stock
      Phenyl(pyridin-2-yl)methanamine|CS-W006043
      39930-11-5

    References

    • BIOVITRUM AB Patent: WO2005/21545 A1, 2005 ; Location in patent: Page/Page column 18 ; WO 2005/021545 A1
  • Route3
    • null|null
      135639-14-4
    • null|null
      591-51-5
    • ~%
    • In-stock
      Phenyl(pyridin-2-yl)methanamine|CS-W006043
      39930-11-5

    References

    • MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE Patent: WO2008/85008 A1, 2008 ; Location in patent: Page/Page column 24-25 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.1297
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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