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CS-W001157 4
Total: USD 88.00

[3-(Morpholin-4-ylmethyl)phenyl]boronic acid

  • CAS No. 397843-58-2

  • Cat. No. CS-0060387
  • Molecule weight221.06
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

[3-(Morpholin-4-ylmethyl)phenyl]boronic acid|CS-0060387

Structure of 397843-58-2

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General Information

  • CAS No. 397843-58-2
  • Cat. No. CS-0060387
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆BNO₃
  • Molecular Weight 221.06
  • Synonym(s) boronic acid, B-[3-(4-morpholinylmethyl)phenyl]-
  • SMILES C1=CC(=CC(=C1)B(O)O)CN2CCOCC2

Description

This boronate moiety integrates a morpholinylmethyl group at the 3-position of a phenyl ring, delivering enhanced solubility and stability under standard conditions. The electron-rich aromatic system facilitates efficient Suzuki-Miyaura coupling, while the pendant morpholine improves handling and compatibility in aqueous environments.

Application

[3-(Morpholin-4-ylmethyl)phenyl]boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its morpholinylmethyl substituent enhances solubility and modulates electronic properties, while the boronic acid group exhibits excellent bench stability and compatibility with diverse functional groups. Ideal for medicinal chemistry and process development workflows requiring robust, predictable coupling performance.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.93
  • LogP   -0.8014
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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