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CS-W001157 4
Total: USD 88.00

1-Oxa-8-azaspiro[4.5]decane hydrochloride

  • CAS No. 3970-79-4

  • Cat. No. CS-B0026
  • Purity≥98%
  • MDL No.MFCD11042294

*For research and further manufacturing use only, not for direct human use.

1-Oxa-8-azaspiro[4.5]decane hydrochloride|CS-B0026

Structure of 3970-79-4

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General Information

  • CAS No. 3970-79-4
  • Cat. No. CS-B0026
  • Purity ≥98%
  • MDL No. MFCD11042294
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆ClNO
  • Molecular Weight 177.67
  • Synonym(s) 8-Aza-1-oxaspiro[4.5]decane hydrochloride
  • SMILES Cl[H].C12(CCNCC2)OCCC1

Description

This spirocyclic amine hydrochloride delivers a rigid, conformationally constrained scaffold ideal for medicinal chemistry applications. The embedded oxazepane ring combines nitrogen heteroatoms with enhanced metabolic stability, enabling efficient integration into bioactive molecules. Its crystalline form ensures reliable handling and reproducible performance in synthetic workflows.

Application

1-Oxa-8-azaspiro[4.5]decane hydrochloride serves as a versatile spirocyclic scaffold for medicinal chemistry campaigns, enabling rapid access to constrained nitrogen-containing heterocycles. Its stability under standard synthetic conditions, combined with orthogonal functionalization potential at the spirocenter and pendant amine, facilitates efficient derivatization in peptide-like and macrocyclic compound development. The hydrochloride salt enhances solubility and handling, supporting routine bench-scale synthesis and purification workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.3408
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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