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CS-W001157 4
Total: USD 88.00

(3R)-3-Methylpyrrolidin-3-ol

  • CAS No. 392338-65-7

  • Cat. No. CS-0053323
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3R)-3-Methylpyrrolidin-3-ol|CS-0053323

Structure of 392338-65-7

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General Information

  • CAS No. 392338-65-7
  • Cat. No. CS-0053323
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) None
  • SMILES C[C@@]1(O)CCNC1

Description

(3R)-3-Methylpyrrolidin-3-ol is a chiral pyrrolidine derivative featuring a stereodefined hydroxyl group and methyl substitution at the 3-position. This configuration imparts enhanced rigidity and defined polarity, enabling selective interactions in asymmetric synthesis. The compound exhibits favorable solubility in polar solvents and stability under standard bench conditions, making it suitable for use in medicinal chemistry and catalyst design.

Application

(3R)-3-Methylpyrrolidin-3-ol serves as a stereochemically defined building block for bioactive heterocycles, offering predictable regioselectivity in cyclization and functionalization reactions. Its bench-stable, crystalline form facilitates handling and purification, while the pendant hydroxyl group enables efficient derivatization—commonly used in medicinal chemistry to access constrained amine scaffolds with improved metabolic stability and target affinity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.2693
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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