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Structure of 720706-28-5
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This acetic acid derivative features a 5-methyl-2H-[1,2,4]triazol-3-yl moiety that imparts enhanced solubility and metabolic stability. The triazole ring enables robust conjugation in bioconjugation workflows, while the carboxylic acid group facilitates straightforward derivatization. This scaffold integrates readily into peptidomimetics and small-molecule probes requiring heterocyclic functionality under standard conditions.
(5-Methyl-2H-[1,2,4]triazol-3-yl)-acetic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. Its triazolyl-acetic acid motif enables efficient conjugation via amide bond formation, offering enhanced metabolic stability and hydrogen-bonding capacity in drug candidates. The molecule exhibits good bench stability, solubility in common organic solvents, and compatibility with standard coupling reagents such as HATU or EDCI. Functions effectively in the construction of triazole-based pharmacophores and bioconjugates.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H226-H302-H412
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P273-P280-P330-P370+P378-P501
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Lot numbers can be found on the outside label of a product: