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CS-W001157 4
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(3-Methoxyphenyl)hydrazine hydrochloride

  • CAS No. 39232-91-2

  • Cat. No. CS-W017475
  • Purity≥95%
  • MDL No.MFCD00044416

*For research and further manufacturing use only, not for direct human use.

(3-Methoxyphenyl)hydrazine hydrochloride|CS-W017475

Structure of 39232-91-2

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General Information

  • CAS No. 39232-91-2
  • Cat. No. CS-W017475
  • Purity ≥95%
  • MDL No. MFCD00044416
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁ClN₂O
  • Molecular Weight 174.63
  • Synonym(s) 3-Methoxyphenylhydrazine hydrochloride
  • SMILES COC1=CC=CC(NN)=C1.Cl

Description

(3-Methoxyphenyl)hydrazine hydrochloride features a phenyl ring bearing both a methoxy and hydrazine functional group, enabling direct incorporation into azo dye and heterocyclic scaffold syntheses. The hydrochloride salt enhances solubility and stability under standard bench conditions, facilitating reliable handling in synthetic workflows.

Application

(3-Methoxyphenyl)hydrazine hydrochloride serves as a reliable building block for the synthesis of diverse heterocyclic scaffolds, particularly in the construction of pyrazoles and triazoles via cycloaddition reactions. Its well-documented reactivity enables efficient coupling with ketones, aldehydes, and electrophilic intermediates under mild conditions. The compound exhibits good bench stability and facilitates straightforward purification, making it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1
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    • ~%
    • In-stock
      (3-Methoxyphenyl)hydrazine hydrochloride|CS-W017475
      39232-91-2

    References

    • Xu, Renbo; Xia, Rui; Luo, Ming; Xu, Xiaoyong; Cheng, Jiagao; Shao, Xusheng; Li, Zhong Journal of Agricultural and Food Chemistry, 2014 , vol. 62, # 2 p. 381 - 390

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   47.28
  • LogP   1.4026
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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