Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Iodo-2-hydroxybenzaldehyde

  • CAS No. 38170-02-4

  • Cat. No. CS-0040703
  • Purity≥98%
  • MDL No.MFCD08457196

*For research and further manufacturing use only, not for direct human use.

4-Iodo-2-hydroxybenzaldehyde|CS-0040703

Structure of 38170-02-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 38170-02-4
  • Cat. No. CS-0040703
  • Purity ≥98%
  • MDL No. MFCD08457196
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅IO₂
  • Molecular Weight 248.02
  • Synonym(s) 2-Hydroxy-4-iodobenzaldehyde
  • SMILES O=CC1=CC=C(I)C=C1O

Description

4-Iodo-2-hydroxybenzaldehyde features a strategically positioned aldehyde group flanked by iodine and phenolic hydroxyl moieties, enabling direct functionalization in cross-coupling and derivatization workflows. The ortho-hydroxyl enhances chelation potential and modulates electronic properties, while the iodo substituent provides a high-reactivity handle for palladium-catalyzed transformations under standard conditions.

Application

4-Iodo-2-hydroxybenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its iodine substituent. The ortho-hydroxyl and aldehyde groups provide orthogonal functionality for sequential transformations, including derivatization via condensation or protection strategies. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for the construction of complex heterocyclic scaffolds and functionalized aromatic intermediates in medicinal chemistry workflows.

Synthesis

  • Route1
    • null|null
      50-00-0
    • In-stock
      2-Iodophenol|CS-W008896
      533-58-4
    • ~79%
    • In-stock
      4-Iodo-2-hydroxybenzaldehyde|CS-0040703
      38170-02-4

    References

    • PHARMACIA and UPJOHN COMPANY LLC Patent: WO2006/40672 A1, 2006 ; Location in patent: Page/Page column 59 ; WO 2006/040672 A1
  • Route2
    • null|null
      50-00-0
    • In-stock
      m-Iodophenol|CS-W007364
      626-02-8
    • ~77%
    • In-stock
      4-Iodo-2-hydroxybenzaldehyde|CS-0040703
      38170-02-4

    References

    • Wang, Jane L.; Limburg, David; Graneto, Matthew J.; Springer, John; Hamper, Joseph Rogier Bruce; Liao, Subo; Pawlitz, Jennifer L.; Kurumbail, Ravi G.; Maziasz, Timothy; Talley, John J.; Kiefer, James R.; Carter, Jeffery Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 23 p. 7159 - 7163
  • Route3

    References

    • MERCK SHARP andamp; DOHME CORP.; MORRIELLO, Gregori, J.; DEVITA, Robert, J.; MILLS, Sander, G.; MOYES, Christopher, R.; LIN, Peter Patent: WO2010/56788 A1, 2010 ; Location in patent: Page/Page column 89-90 ; WO 2010/056788 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.8093
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Iodo-2-hydroxybenzaldehyde sigma4-Iodo-2-hydroxybenzaldehyde manufacturer4-Iodo-2-hydroxybenzaldehyde price4-Iodo-2-hydroxybenzaldehyde structure4-Iodo-2-hydroxybenzaldehyde SDSbuy 4-Iodo-2-hydroxybenzaldehyde4-Iodo-2-hydroxybenzaldehyde supplier4-Iodo-2-hydroxybenzaldehyde uses4-Iodo-2-hydroxybenzaldehyde molecular weightprice of 4-Iodo-2-hydroxybenzaldehyde4-Iodo-2-hydroxybenzaldehyde chemical name formula of 4-Iodo-2-hydroxybenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label