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CS-W001157 4
Total: USD 88.00

4-Hydroxybenzamidine hydrochloride

  • CAS No. 38148-63-9

  • Cat. No. CS-W017570
  • Purity≥98%
  • MDL No.MFCD00136405

*For research and further manufacturing use only, not for direct human use.

4-Hydroxybenzamidine hydrochloride|CS-W017570

Structure of 38148-63-9

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General Information

  • CAS No. 38148-63-9
  • Cat. No. CS-W017570
  • Purity ≥98%
  • MDL No. MFCD00136405
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉ClN₂O
  • Molecular Weight 172.61
  • Synonym(s) p-Hydroxybenzamidine hydrochloride; 4-Hydroxybenzamidine hydrochloride
  • SMILES NC(C1=CC=C(O)C=C1)=N.Cl

Description

4-Hydroxybenzamidine hydrochloride features a phenolic hydroxyl group and amidine functionality, offering enhanced solubility and stability under standard conditions. This bifunctional scaffold enables direct integration into bioactive molecules, serving as a key intermediate in the synthesis of kinase inhibitors and other pharmaceutical candidates.

Application

4-Hydroxybenzamidine hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its amidine functionality enables efficient coupling reactions and acts as a hydrogen-bonding motif in target-directed design. The phenolic hydroxyl group offers additional handle for derivatization, while the hydrochloride salt ensures excellent bench stability and ease of purification in standard organic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   70.1
  • LogP   1.09807
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   1

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