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Structure of 378211-85-9
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Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 2-position, enabling direct conjugation or derivatization. This scaffold combines electron-deficient aromaticity with hydrogen-bonding capacity, offering utility in medicinal chemistry and materials science applications.
Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard coupling reactions. Its carboxylic acid functionality facilitates direct derivatization or amide formation under mild conditions, while the fused pyrazolo[1,5-a]pyrimidine core exhibits good bench stability and functional group tolerance. This compound functions as a key intermediate in the construction of kinase inhibitors and other pharmacologically relevant architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: