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CS-W001157 4
Total: USD 88.00

3-(Benzyloxy)phenol

  • CAS No. 3769-41-3

  • Cat. No. CS-W019380
  • Purity≥95%
  • MDL No.MFCD00134682

*For research and further manufacturing use only, not for direct human use.

3-(Benzyloxy)phenol|CS-W019380

Structure of 3769-41-3

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General Information

  • CAS No. 3769-41-3
  • Cat. No. CS-W019380
  • Purity ≥95%
  • MDL No. MFCD00134682
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂O₂
  • Molecular Weight 200.23
  • Synonym(s) Resorcinol Monobenzyl Ether
  • SMILES OC1=CC(OCC2=CC=CC=C2)=CC=C1

Description

3-(Benzyloxy)phenol features a phenolic hydroxyl group flanked by a benzyloxy substituent, offering enhanced solubility and stability compared to simple phenols. This combination enables direct use in synthetic transformations without protection, streamlining access to functionalized aryl scaffolds in medicinal chemistry and materials development.

Application

3-(Benzyloxy)phenol serves as a versatile building block in medicinal chemistry and materials synthesis, enabling direct access to substituted benzyl ethers and phenolic scaffolds. Its benzyloxy group offers orthogonal protection for phenolic hydroxyls under acidic conditions, while the free phenol facilitates further functionalization via electrophilic substitution or coupling reactions. The molecule exhibits good bench stability and is compatible with standard purification methods, making it ideal for multi-step synthetic sequences.

Synthesis

  • Route1
    • null|null
      100-39-0
    • null|null
      108-46-3
    • ~78%
    • In-stock
      3-(Benzyloxy)phenol|CS-W019380
      3769-41-3

    References

    • Frlan, Rok; Gobec, Stanislav; Kikelj, Danijel Tetrahedron, 2007 , vol. 63, # 43 p. 10698 - 10708
  • Route2

    References

    • Maleski; Kluge; Sicker Synthetic Communications, 1995 , vol. 25, # 15 p. 2327 - 2335
  • Route3
    • null|null
      100-44-7
    • null|null
      108-46-3
    • ~72%
    • In-stock
      3-(Benzyloxy)phenol|CS-W019380
      3769-41-3

    References

    • Balamurugan; Kannan; Yadupati; Roy Journal of Molecular Structure, 2011 , vol. 1001, # 1-3 p. 118 - 124

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   2.9712
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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