(R)-2-Chloropropan-1-ol

Name: (R)-2-Chloropropan-1-ol
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CAS No. 37493-14-4
Cat. No. CS-0186126
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 37493-14-4
Cat. No. CS-0186126
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₇ClO
Molecular Weight 94.54
Synonym(s) 1-PROPANOL, 2-CHLORO-, (2R)-
SMILES C[C@H](CO)Cl

Description

(R)-2-Chloropropan-1-ol is a chiral synthon featuring a stereodefined hydroxyl group and a chlorine atom on adjacent carbons. This configuration enables selective functionalization in asymmetric synthesis, particularly in the construction of enantiopure intermediates for pharmaceuticals and agrochemicals. The molecule exhibits enhanced stability under standard handling conditions and integrates readily into multi-step sequences requiring stereocontrol.

Application

(R)-2-Chloropropan-1-ol serves as a valuable chiral building block in synthetic organic chemistry, enabling stereoselective transformations through its reactive primary alcohol and adjacent chiral center. Its bench-stable nature and compatibility with common functional groups facilitate straightforward incorporation into complex molecules, including pharmaceutical intermediates and agrochemical scaffolds. The compound functions effectively in nucleophilic substitution reactions and as a precursor for enantioselective synthesis.

Safety Information

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GHS Pictogram :	GHS No : GHS02,GHS07
Signal Word : Danger	UN#: 1993
Class : 3	Packing Group : Ⅱ
Hazard Statements : H226-H302+H312+H332-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

TPSA 20.23
LogP 0.606
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty chain compounds

Key Words

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(R)-2-Chloropropan-1-ol

CAS No. 37493-14-4

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