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CS-W001157 4
Total: USD 88.00

(4-Bromo-3-fluorophenyl)boronic acid

  • CAS No. 374790-97-3

  • Cat. No. CS-0113170
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD02093066

*For research and further manufacturing use only, not for direct human use.

(4-Bromo-3-fluorophenyl)boronic acid|CS-0113170

Structure of 374790-97-3

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General Information

  • CAS No. 374790-97-3
  • Cat. No. CS-0113170
  • Purity ≥97%
  • MDL No. MFCD02093066
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BBrFO₂
  • Molecular Weight None
  • Synonym(s) 4-Bromo-3-fluorobenzeneboronic acid
  • SMILES BrC1=CC=C(B(O)O)C=C1F

Description

This boronate moiety enables direct coupling in Suzuki-Miyaura reactions, offering enhanced reactivity and stability under standard conditions. The ortho-bromo and meta-fluoro substituents provide complementary functional handles for sequential derivatization, while the bench-stable nature simplifies handling and storage.

Application

(4-Bromo-3-fluorophenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki-Miyaura conditions. Its compatibility with diverse functional groups and robust bench stability make it ideal for constructing complex aryl scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.268
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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