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CS-W001157 4
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Methyl tetrahydrofuran-2-carboxylate

  • CAS No. 37443-42-8

  • Cat. No. CS-0096501
  • Purity≥98%
  • MDL No.MFCD00154541

*For research and further manufacturing use only, not for direct human use.

Methyl tetrahydrofuran-2-carboxylate|CS-0096501

Structure of 37443-42-8

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General Information

  • CAS No. 37443-42-8
  • Cat. No. CS-0096501
  • Purity ≥98%
  • MDL No. MFCD00154541
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₃
  • Molecular Weight 130.14
  • Synonym(s) Tetrahydro-furan-2-carboxylic acid methyl ester
  • SMILES O=C(OC)C1CCCO1

Description

Methyl tetrahydrofuran-2-carboxylate is a bench-stable, moisture-tolerant heterocyclic ester featuring a fused tetrahydrofuran ring that enables efficient incorporation into complex molecular architectures. This compound serves as a key building block in synthetic organic chemistry, particularly for constructing chiral scaffolds and bioactive intermediates under standard conditions.

Application

Methyl tetrahydrofuran-2-carboxylate serves as a versatile chiral building block in synthetic organic chemistry, enabling efficient access to functionalized heterocycles and bioactive scaffolds. Its cyclic ester structure provides enhanced bench stability and facilitates selective transformations, including nucleophilic ring-opening and stereoselective derivatization. The molecule functions as a key intermediate in the synthesis of γ-lactone-containing compounds and supports orthogonal reactivity in complex molecule assembly.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H318
Precautionary Statements : P210-P280-P370+P378-P403-P501

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   0.3384
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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