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CS-W001157 4
Total: USD 88.00

4-Fluoro-3-Nitrobenzotrifluoride

  • CAS No. 367-86-2

  • Cat. No. CS-W015173
  • Purity≥98%
  • MDL No.MFCD00007059

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-3-Nitrobenzotrifluoride|CS-W015173

Structure of 367-86-2

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General Information

  • CAS No. 367-86-2
  • Cat. No. CS-W015173
  • Purity ≥98%
  • MDL No. MFCD00007059
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃F₄NO₂
  • Molecular Weight 209.10
  • Synonym(s) 4-fluoro-3-nitro-α,α,α-trifluorotoluene
  • SMILES FC(F)(F)C1=CC=C(F)C([N+]([O-])=O)=C1

Description

4-Fluoro-3-nitrobenzotrifluoride was used in the pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines. It may be used as derivatization reagent for the HPLC determination of polyamines (spermidine, spermine and the diamine precursor putrescine). It was also used in the synthesis of:2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids[3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one

Synthesis

  • Route1
    • null|null
      121-17-5
    • ~81%
    • In-stock
      4-Fluoro-3-Nitrobenzotrifluoride|CS-W015173
      367-86-2

    References

    • Maggini, Michele; Passudetti, Margherita; Gonzales-Trueba, Guadalupe; Prato, Maurizio; Quintily, Ugo; Scorrano, Gianfranco Journal of Organic Chemistry, 1991 , vol. 56, # 22 p. 6406 - 6411
  • Route2
    • null|null
      402-44-8
    • ~%
    • In-stock
      4-Fluoro-3-Nitrobenzotrifluoride|CS-W015173
      367-86-2

    References

    • Kuhn,J.; Olah,G.A. Journal of the American Chemical Society, 1961 , vol. 83, p. 4564 - 4571
  • Route3
    • null|null
      121-17-5
    • ~%
    • In-stock
      4-Fluoro-3-Nitrobenzotrifluoride|CS-W015173
      367-86-2
    • null|null
      346-41-8

    References

    • Finger; Kruse Journal of the American Chemical Society, 1956 , vol. 78, p. 6034,6037

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.14
  • LogP   2.7527
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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