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CS-W001157 4
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N-Carbobenzyloxy-amino-L-alanine

  • CAS No. 35761-26-3

  • Cat. No. CS-W002578
  • Purity≥97%
  • MDL No.MFCD00237345

*For research and further manufacturing use only, not for direct human use.

N-Carbobenzyloxy-amino-L-alanine|CS-W002578

Structure of 35761-26-3

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General Information

  • CAS No. 35761-26-3
  • Cat. No. CS-W002578
  • Purity ≥97%
  • MDL No. MFCD00237345
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂O₄
  • Molecular Weight 238.24
  • Synonym(s) None
  • SMILES O=C([C@@H](NC(OCC1=CC=CC=C1)=O)CN)O

Description

N-Carbobenzyloxy-L-alanine features a stable, bench-ready carbobenzyloxy protecting group that enables efficient peptide chain elongation. The α-amino functionality integrates seamlessly into synthetic sequences, while the benzyl-protected nitrogen resists premature deprotonation. This derivative supports high-yielding coupling reactions under standard conditions.

Synthesis

  • Route1

    References

    • Dobrovinskaya, Nina A.; Archer; Hulme, Alison N. Synlett, 2008 , # 4 p. 513 - 516
  • Route2

    References

    • Ratemi, Elaref S.; Vederas, John C. Tetrahedron Letters, 1994 , vol. 35, # 41 p. 7605 - 7608
  • Route3
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    References

    • Mokotoff; Logue Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 554 - 559

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   0.3247
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   5

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