Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Methylpropane-2-sulfonamide

  • CAS No. 34813-49-5

  • Cat. No. CS-W004736
  • Purity≥97%
  • MDL No.MFCD02179404

*For research and further manufacturing use only, not for direct human use.

2-Methylpropane-2-sulfonamide|CS-W004736

Structure of 34813-49-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 34813-49-5
  • Cat. No. CS-W004736
  • Purity ≥97%
  • MDL No. MFCD02179404
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁NO₂S
  • Molecular Weight 137.20
  • Synonym(s) tert-Butylsulfonamide
  • SMILES C(C)(C)(C)[S](=O)(=O)N

Description

2-Methylpropane-2-sulfonamide is a sterically hindered sulfonamide featuring a tertiary carbon center, enhancing its stability and resistance to hydrolysis. This structural rigidity facilitates its use in bioactive molecule design, particularly as a metabolically stable amide surrogate in medicinal chemistry applications.

Application

2-Methylpropane-2-sulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and process development. Its tertiary sulfonamide functionality exhibits excellent functional group tolerance and facilitates efficient coupling reactions in peptide and heterocyclic synthesis. The bulky tert-butyl-like structure enhances metabolic stability and modulates physicochemical properties in API candidates.

Synthesis

  • Route1

    References

    • Garcia Ruano, Jose Luis; Parra, Alejandro; Yuste, Francisco; Mastranzo, Virginia M. Synthesis, 2008 , # 2 p. 311 - 319
  • Route2
    • null|null
      31562-43-3
    • ~89%
    • In-stock
      2-Methylpropane-2-sulfonamide|CS-W004736
      34813-49-5

    References

    • Schleusner, Marcel; Koep, Stefan; Guenter, Markus; Tiwari, Shashi K.; Gais, Hans-Joachim Synthesis, 2004 , # 6 p. 967 - 969
  • Route3
    • null|null
      10490-22-9
    • ~%
    • In-stock
      2-Methylpropane-2-sulfonamide|CS-W004736
      34813-49-5

    References

    • DR. REDDY'S LABORATORIES LTD.; SASMAL, Pradip Kumar; AHMED, Shahadat; TEHIM, Ashok; PRADKAR, Vidyadhar; DATTATREYA, Prasanna M.; MAVINAHALLI, Nanjegowda Jagadeesh Patent: WO2013/88256 A1, 2013 ; Location in patent: Page/Page column 62 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.16
  • LogP   0.0734
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Methylpropane-2-sulfonamide sigma2-Methylpropane-2-sulfonamide manufacturer2-Methylpropane-2-sulfonamide price2-Methylpropane-2-sulfonamide structure2-Methylpropane-2-sulfonamide SDSbuy 2-Methylpropane-2-sulfonamide2-Methylpropane-2-sulfonamide supplier2-Methylpropane-2-sulfonamide uses2-Methylpropane-2-sulfonamide molecular weightprice of 2-Methylpropane-2-sulfonamide2-Methylpropane-2-sulfonamide chemical name formula of 2-Methylpropane-2-sulfonamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label