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CS-W001157 4
Total: USD 88.00

2-Amino-6-ethylbenzoic acid

  • CAS No. 66232-56-2

  • Cat. No. CS-D0143
  • Purity≥98%
  • MDL No.MFCD11616258

*For research and further manufacturing use only, not for direct human use.

2-Amino-6-ethylbenzoic acid|CS-D0143

Structure of 66232-56-2

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General Information

  • CAS No. 66232-56-2
  • Cat. No. CS-D0143
  • Purity ≥98%
  • MDL No. MFCD11616258
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) None
  • SMILES O=C(O)C1=C(CC)C=CC=C1N

Description

2-Amino-6-ethylbenzoic acid features a strategically positioned amino group and ethyl substituent on the benzoic acid scaffold, enabling enhanced solubility and tunable reactivity. This combination supports efficient derivatization in synthetic routes targeting bioactive molecules and functional materials.

Application

2-Amino-6-ethylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-amino and carboxylic acid functionalities offer complementary reactivity for amide coupling, cyclization, and metal-catalyzed transformations. The ethyl group enhances lipophilicity and modulates electronic effects, while the compound exhibits good bench stability and ease of purification—ideal for scalable route development and API precursor synthesis.

Synthesis

  • Route1
    • null|null
      13619-67-5
    • ~95%
    • In-stock
      2-Amino-6-ethylbenzoic acid|CS-D0143
      66232-56-2

    References

    • Active Biotech AB Patent: EP2316818 A1, 2011 ; Location in patent: Page/Page column 6-7 ;
  • Route2
    • 2-Acetyl-6-nitrobenzoic acid|CS-1682968
      13619-70-0
    • ~%
    • null|null
      148843-77-0
    • In-stock
      2-Amino-6-ethylbenzoic acid|CS-D0143
      66232-56-2

    References

    • Pest Management Science, , vol. 57, # 3 p. 205 - 224
  • Route3
    • null|null
      148843-77-0
    • ~97%
    • In-stock
      2-Amino-6-ethylbenzoic acid|CS-D0143
      66232-56-2

    References

    • ACTIVE BIOTECH AB; JANSSON, Karl Patent: WO2011/54874 A1, 2011 ; Location in patent: Page/Page column 10; 11 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.5294
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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