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Structure of 3438-61-7
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4-Methylpyrimidin-5-amine features a pyrimidine core with a methyl group at the 4-position and an amino function at the 5-position, delivering enhanced electron density for nucleophilic engagement. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, offering robust reactivity under standard conditions.
4-Methylpyrimidin-5-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. Its amine functionality facilitates direct coupling reactions and derivatization, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and is compatible with standard synthetic protocols, including Suzuki-Miyaura and Buchwald-Hartwig couplings. It functions as a key intermediate in the development of kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: