Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Chloro-4-methylpyrimidin-5-amine

  • CAS No. 20090-69-1

  • Cat. No. CS-W019804
  • Purity≥98%
  • MDL No.MFCD12923128

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4-methylpyrimidin-5-amine|CS-W019804

Structure of 20090-69-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 20090-69-1
  • Cat. No. CS-W019804
  • Purity ≥98%
  • MDL No. MFCD12923128
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆ClN₃
  • Molecular Weight 143.57
  • Synonym(s) 2-Chloro-4-methyl-5-pyrimidinamine; 2-Chloro-4-methylpyrimidin-5-amine; NSC 243816; 5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)
  • SMILES NC1=CN=C(Cl)N=C1C

Description

2-Chloro-4-methylpyrimidin-5-amine delivers a reactive chloro handle and an electron-rich amine site within a stable pyrimidine scaffold. This bifunctional heterocycle integrates efficiently into medicinal chemistry campaigns, enabling rapid diversification through nucleophilic substitution or coupling reactions under standard conditions.

Application

2-Chloro-4-methylpyrimidin-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its chloro group facilitates nucleophilic substitution reactions, while the amino and methyl functionalities offer orthogonal handles for further functionalization. The compound exhibits good bench stability and is compatible with standard coupling protocols, making it well-suited for modular synthesis of kinase inhibitors and other bioactive heterocycles.

Synthesis

  • Route1

    References

    • Chemische Berichte, , vol. 34, p. 1242
  • Route2

    References

    • US2009/93472 A1, ; Page/Page column 23-24 ; US 20090093472 A1
  • Route3
    • In-stock
      2,4-Dichloro-6-methyl-5-nitropyrimidine|CS-D1701
      13162-26-0
    • null|null
      7732-18-5
    • ~%
    • In-stock
      2-Chloro-4-methylpyrimidin-5-amine|CS-W019804
      20090-69-1

    References

    • Chemische Berichte, , vol. 34, p. 1242

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.02062
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Chloro-4-methylpyrimidin-5-amine sigma2-Chloro-4-methylpyrimidin-5-amine manufacturer2-Chloro-4-methylpyrimidin-5-amine price2-Chloro-4-methylpyrimidin-5-amine structure2-Chloro-4-methylpyrimidin-5-amine SDSbuy 2-Chloro-4-methylpyrimidin-5-amine2-Chloro-4-methylpyrimidin-5-amine supplier2-Chloro-4-methylpyrimidin-5-amine uses2-Chloro-4-methylpyrimidin-5-amine molecular weightprice of 2-Chloro-4-methylpyrimidin-5-amine2-Chloro-4-methylpyrimidin-5-amine chemical name formula of 2-Chloro-4-methylpyrimidin-5-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label