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CS-W001157 4
Total: USD 88.00

5-Amino-2-picoline

  • CAS No. 3430-14-6

  • Cat. No. CS-W009257
  • Purity≥97%
  • MDL No.MFCD00833389

*For research and further manufacturing use only, not for direct human use.

5-Amino-2-picoline|CS-W009257

Structure of 3430-14-6

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General Information

  • CAS No. 3430-14-6
  • Cat. No. CS-W009257
  • Purity ≥97%
  • MDL No. MFCD00833389
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂
  • Molecular Weight 108.14
  • Synonym(s) 5-Amino-2-methylpyridine
  • SMILES CC1=CC=C(N)C=N1

Description

5-Amino-2-picoline delivers a strategically positioned amino group on a picolyl scaffold, enabling direct incorporation into heterocyclic architectures. This electron-rich derivative facilitates efficient coupling reactions and exhibits enhanced solubility in polar media, supporting its use in synthetic intermediates for pharmaceutical and agrochemical development under standard conditions.

Application

5-Amino-2-picoline serves as a versatile building block in medicinal chemistry and catalysis, offering a pyridine core with ortho-amino and methyl substituents that enable diverse functionalization. Its amino group facilitates direct coupling reactions and metal coordination, while the methyl group provides a handle for oxidation or C–H activation. The compound exhibits good bench stability and compatibility with standard synthetic workflows, enabling efficient access to substituted heterocycles and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.97222
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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