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CS-W001157 4
Total: USD 88.00

5-Hydroxyoxindole

  • CAS No. 3416-18-0

  • Cat. No. CS-W001542
  • Purity≥95%
  • MDL No.MFCD00014566

*For research and further manufacturing use only, not for direct human use.

5-Hydroxyoxindole|CS-W001542

Structure of 3416-18-0

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General Information

  • CAS No. 3416-18-0
  • Cat. No. CS-W001542
  • Purity ≥95%
  • MDL No. MFCD00014566
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₂
  • Molecular Weight 149.15
  • Synonym(s) None
  • SMILES O=C1NC2=C(C=C(O)C=C2)C1

Description

5-Hydroxyoxindole features a hydroxyl group at the C5 position of the oxindole core, enhancing its polarity and enabling direct participation in hydrogen bonding. This structural motif supports integration into bioactive molecule scaffolds, particularly in kinase inhibitor design and fluorescent probe development. The compound exhibits bench-stable handling characteristics under standard conditions.

Application

5-Hydroxyoxindole serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard functional group manipulations. Its phenolic hydroxyl and carbonyl groups provide orthogonal reactivity for derivatization, while the oxindole core offers structural rigidity and hydrogen-bonding capacity relevant to target binding. The compound exhibits good bench stability and facilitates efficient purification via recrystallization or chromatography, making it well-suited for scalable synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.8868
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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