Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Iodo-1-methyl-1H-pyrazole

  • CAS No. 34091-51-5

  • Cat. No. CS-D0852
  • Purity≥96%
  • MDL No.MFCD11109327

*For research and further manufacturing use only, not for direct human use.

5-Iodo-1-methyl-1H-pyrazole|CS-D0852

Structure of 34091-51-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 34091-51-5
  • Cat. No. CS-D0852
  • Purity ≥96%
  • MDL No. MFCD11109327
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅IN₂
  • Molecular Weight 208.00
  • Synonym(s) 1-Methyl-5-iodopyrazole
  • SMILES CN1N=CC=C1I

Description

5-Iodo-1-methyl-1H-pyrazole is a bench-stable heterocyclic reagent featuring a iodinated pyrazole core with a methyl group at the 1-position. This configuration enables direct coupling in transition-metal-catalyzed transformations, particularly Suzuki-Miyaura and Sonogashira reactions. The electron-deficient nature of the ring enhances reactivity in cross-coupling protocols. Its moisture-tolerant handling simplifies integration into synthetic workflows.

Application

5-Iodo-1-methyl-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Sonogashira transformations. The iodide functionality provides high reactivity under standard conditions, while the 1-methylpyrazole core offers excellent bench stability and compatibility with diverse functional groups. This compound facilitates efficient access to substituted pyrazole scaffolds prevalent in bioactive molecules and drug discovery programs.

Synthesis

  • Route1
    • null|null
      930-36-9
    • ~87%
    • In-stock
      5-Iodo-1-methyl-1H-pyrazole|CS-D0852
      34091-51-5

    References

    • Blair, Victoria L.; Blakemore, David C.; Hay, Duncan; Hevia, Eva; Pryde, David C. Tetrahedron Letters, 2011 , vol. 52, # 36 p. 4590 - 4594
  • Route2
    • null|null
      930-36-9
    • ~3%
    • null|null
      92525-20-7
    • null|null
      92525-19-4
    • In-stock
      5-Iodo-1-methyl-1H-pyrazole|CS-D0852
      34091-51-5

    References

    • Journal of Organic Chemistry, , vol. 49, # 24 p. 4687 - 4695

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.0247
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Iodo-1-methyl-1H-pyrazole sigma5-Iodo-1-methyl-1H-pyrazole manufacturer5-Iodo-1-methyl-1H-pyrazole price5-Iodo-1-methyl-1H-pyrazole structure5-Iodo-1-methyl-1H-pyrazole SDSbuy 5-Iodo-1-methyl-1H-pyrazole5-Iodo-1-methyl-1H-pyrazole supplier5-Iodo-1-methyl-1H-pyrazole uses5-Iodo-1-methyl-1H-pyrazole molecular weightprice of 5-Iodo-1-methyl-1H-pyrazole5-Iodo-1-methyl-1H-pyrazole chemical name formula of 5-Iodo-1-methyl-1H-pyrazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label