Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Iodoquinazoline

  • CAS No. 848841-54-3

  • Cat. No. CS-0097948
  • Purity≥96%
  • MDL No.MFCD09834646

*For research and further manufacturing use only, not for direct human use.

6-Iodoquinazoline|CS-0097948

Structure of 848841-54-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 848841-54-3
  • Cat. No. CS-0097948
  • Purity ≥96%
  • MDL No. MFCD09834646
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅IN₂
  • Molecular Weight 256.04
  • Synonym(s) Quinazoline, 6-iodo-
  • SMILES IC1=CC2=CN=CN=C2C=C1

Description

6-Iodoquinazoline serves as a key electrophilic scaffold in transition-metal-catalyzed cross-coupling reactions. The iodine substituent enables efficient Pd- or Ni-mediated functionalization, facilitating the construction of complex quinazoline derivatives. This bench-stable compound integrates readily into pharmaceutical and agrochemical synthesis workflows.

Application

6-Iodoquinazoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. Its iodine substituent provides high reactivity in standard Suzuki, Stille, and Negishi couplings, while the quinazoline core offers excellent stability and compatibility with diverse functional groups. This compound facilitates efficient synthesis of kinase inhibitors and other bioactive molecules, offering predictable reactivity and straightforward purification.

Synthesis

  • Route1

    References

    • NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2005/28444 A1, 2005 ; Location in patent: Page/Page column 56 ; WO 2005/028444 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.2344
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Iodoquinazoline sigma6-Iodoquinazoline manufacturer6-Iodoquinazoline price6-Iodoquinazoline structure6-Iodoquinazoline SDSbuy 6-Iodoquinazoline6-Iodoquinazoline supplier6-Iodoquinazoline uses6-Iodoquinazoline molecular weightprice of 6-Iodoquinazoline6-Iodoquinazoline chemical name formula of 6-Iodoquinazoline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label