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CS-W001157 4
Total: USD 88.00

Boc-Leu-OSu

  • CAS No. 3392-09-4

  • Cat. No. CS-0154136
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Boc-Leu-OSu|CS-0154136

Structure of 3392-09-4

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General Information

  • CAS No. 3392-09-4
  • Cat. No. CS-0154136
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₄N₂O₆
  • Molecular Weight 328.36
  • Synonym(s) N-TERT-BUTOXYCARBONYL-L-LEUCINE-N-HYDROXYSUCCINIMIDE ESTER
  • SMILES CC(C[C@H](NC(OC(C)(C)C)=O)C(ON1C(CCC1=O)=O)=O)C

Description

Boc-Leu-OSu delivers a protected leucine residue with high reactivity for peptide synthesis. The orthoester-activated ester facilitates rapid coupling under mild conditions, while the Boc group ensures stable N-terminal protection. This reagent streamlines chain elongation in solid-phase and solution-phase workflows.

Synthesis

  • Route1

    References

    • DeGraw, Joseph I.; Almquist, Ronald G.; Hiebert, Charles K.; Colwell, William T.; Crase, Jac; Hayano, Takeshi; Judd, Amrit K.; Dousman, Linda; Smith, R. Lane; Waud, William R.; Uchida, Itsuo Journal of Medicinal Chemistry, 1997 , vol. 40, # 15 p. 2386 - 2397

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   102.01
  • LogP   1.533
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   5

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