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CS-W001157 4
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Bromodifluoroacetic acid

  • CAS No. 354-08-5

  • Cat. No. CS-0121135
  • Purity≥97%
  • MDL No.MFCD02183519

*For research and further manufacturing use only, not for direct human use.

Bromodifluoroacetic acid|CS-0121135

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General Information

  • CAS No. 354-08-5
  • Cat. No. CS-0121135
  • Purity ≥97%
  • MDL No. MFCD02183519
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂HBrF₂O₂
  • Molecular Weight 174.93
  • Synonym(s) Difluorobromoacetic acid
  • SMILES O=C(O)C(F)(Br)F

Description

Bromodifluoroacetic acid is a highly reactive fluorinated carboxylic acid featuring a bromine atom and two fluorine atoms directly attached to the alpha carbon. This configuration imparts strong electron-withdrawing character, enhancing its utility in synthetic transformations requiring high electrophilicity. The compound serves as a key building block in the development of fluorinated pharmaceutical intermediates and specialty polymers.

Synthesis

  • Route1

    References

    • US2003/32836 A1, ;
  • Route2
    • null|null
      354-51-8
    • ~65%
    • In-stock
      Bromodifluoroacetic acid|CS-0121135
      354-08-5

    References

    • Hu, Chang-Ming; Qing, Feng-Ling; Zhang, Hong-Gen Journal of Fluorine Chemistry, 1990 , vol. 49, # 2 p. 275 - 280
  • Route3
    • null|null
      764-06-7
    • ~%
    • In-stock
      Bromodifluoroacetic acid|CS-0121135
      354-08-5

    References

    • Journal of the American Chemical Society, , vol. 81, p. 5256

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P280-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.0587
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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