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CS-W001157 4
Total: USD 88.00

1-(2-Bromoethyl)-4-fluorobenzene

  • CAS No. 332-42-3

  • Cat. No. CS-D1609
  • Molecule weight203.05
  • Purity≥97%
  • MDL No.MFCD03844794

*For research and further manufacturing use only, not for direct human use.

1-(2-Bromoethyl)-4-fluorobenzene|CS-D1609

Structure of 332-42-3

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General Information

  • CAS No. 332-42-3
  • Cat. No. CS-D1609
  • Purity ≥97%
  • MDL No. MFCD03844794
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BrF
  • Molecular Weight 203.05
  • Synonym(s) 1-Bromo-2-(4-fluorophenyl)ethane; 2-(4-Fluorophenyl)ethyl bromide; 2-(p-Fluorophenyl)ethyl bromide; Benzene, 1-(2-bromoethyl)-4-fluoro-
  • SMILES FC1=CC=C(CCBr)C=C1

Description

1-(2-Bromoethyl)-4-fluorobenzene is a fluorinated aryl alkyl bromide featuring a reactive bromoethyl handle. This electrophilic site enables efficient coupling in cross-coupling reactions, while the para-fluoro substituent enhances electron-withdrawal and metabolic stability. The molecule exhibits excellent bench stability and compatibility with diverse reaction conditions.

Synthesis

  • Route1

    References

    • Morris, David J.; Hayes, Aidan M.; Wills, Martin Journal of Organic Chemistry, 2006 , vol. 71, # 18 p. 7035 - 7044
  • Route2

    References

    • US5677324 A1, ; US 5677324 A
  • Route3
    • In-stock
      2-(4-Fluorophenyl)ethanol|CS-W004152
      7589-27-7
    • null|null
      7789-60-8
    • ~31%
    • In-stock
      1-(2-Bromoethyl)-4-fluorobenzene|CS-D1609
      332-42-3

    References

    • Daugs, Edward D.; Evans, Jonathan C.; Flemming, Hans-Wolfram; Hilpert, Thomas Heinz Eduard; Koek, Johannes Nicolaas; Laskovics, Frederick M.; Stolz-Dunn, Sandra K.; Tomlinson, Ian A. Patent: US2002/151717 A1, 2002 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H411
Precautionary Statements : P264-P270-P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.7631
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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